Haemoglobin

Intended Use

Biostep Diagnostic’s haemoglobin reagent is intended for the invitro quantitative, diagnostic determination of haemoglobin in human blood.

Background

Haemoglobin (Hb) is the red pigmented protein located in the erythrocytes and consists of four subunits. Its main function is the transport of oxygen and carbon dioxide in blood. In normal human adults, at least 96 % of the haemoglobin is HbA. HbA2 is usually about 2.5 – 3 % of total haemoglobin. Fetal hemoglobin (HbF) predominates during fetal life and diminishes rapidly during the first year of postnatal life. In normal adults less than 1 % is HbF.Blood haemoglobin concentration may be diminished as a consequence of hemorrhage or hemolysis or as a result of impaired blood formation in the bone marrow.