CRP + Calibrator

Intended Use

In vitro diagnostic reagents for the quantitative determination of C Reactive Protein (CRP) in human serum by means of particle enhanced turbidimetric immunoassay.

Background

C- reactive protein (CRP) is one of the acute phase proteins being synthesized by hepatocytes. The serum concentration of CRP increases during acute stages of diverse diseases associated with inflammation and tissue injury. Elevated CRP has been demonstrated in nearly all bacterial and fungal infections. In addition, it has been shown to be increased in other diseases as neoplasia and rheumatic diseases as well as in major surgery. The diagnosis usefulness of CRP is based on the velocity and on the magnitude of its increase.

Serum concentrations are raised within hours of disease onset and the increase can be as much 2000-fold. A rapid fall of CRP levels indicates recovery.